User Verification of Precision and Estimation of Bias Preliminary Evaluation of Quantitative Clinical Laboratory Measurement Procedures and
day, run, laboratory), and 1 fixed factor (e.g. Flexible balanced and unbalanced experiment design: up to 3 random nested factors new in 4.60 (e.g.Unified analysis to examine performance characteristics of a method (bias, precision, linearity, interferences, and detection limits).Measurement Procedure Comparison and Bias Estimation Using Patient SamplesĮstimation of Total Analytical Error for Clinical Laboratory Methods
Precision (SD or CV) and precision plots for each method.CUSUM linearity plot and Kolmogorov-Smirnov linearity test.Residual plot, raw and standardized, with histogram of residuals.Mountain plot with allowable difference band new in v3.71.Bland-Altman limits of agreement with mean, median, and linear fit bias new in v3.75.Difference/relative difference/ratio plot against X or mean of methods with allowable difference band and histogram of differences.Scatter plot, with average bias, average bias confidence bands, identity line, and allowable difference band.Test equality (no difference) or equivalence (difference within an allowable difference) at decision levels.Predict bias with confidence intervals at important decision levels.Passing Bablok regression average bias with Passing-Bablok or Bootstrap confidence.Deming and Weighted Deming regression average bias with Jacknife confidence intervals.Ordinary and Weighted linear regression average bias with confidence intervals.constant / relative differences) new in v4.00 Reduce measuring interval to linear range, or partition into multiple intervals with different relationships (e.g.Compare commutability of samples with prediction intervals new in v4.90.Supports singlicate, duplicate, and replicate measurements.